This is a cartoon about one of the presidential candidates, Mitt Romney. He is being confronted by four extremely rich characters: the Monopoly man, Richy Rich, Scrooge McDuck, and Mr.Burns. These characters are looking at Mitt Romney angrily as if he had done something wrong. These characters are insanely wealthy and are known to be pretty selfish, especially when it comes to money. They don't care about other's well being unless it will negatively affect them. (This description mostly applies to Mr. Burns and Scrooge McDuck. I think Richy Rich and the Monopoly man are just there to get the point across.) To have these characters who are so selfish telling Romney that he's making them look bad, then there has to be something wrong with him.
After a little research about this cartoon, I found out that this was in response to what he said in an interview. "I’m not concerned about the very poor. We have a safety net there. If it needs repair, I’ll fix it. ... I’m not concerned about the very rich, they’re doing just fine."
What I understand from what he said, he's mostly concerned with the middle class who, according to him, were hit the hardest with the economic downturn. Which means that he will be focusing most of his attention to the middle class and leave the poor and the rich in the dust. Now, he did mention that only the ones who were in that "safety net" he wasn't worried about, which could mean that he would help the people who weren't in it, but even so I think the people who are either rich or poor won't be too happy about his response.